Good Morning! Thanks for responding, . Hoping with Humira, the pain eases for you. It takes time to work and you should have results after 3-4 months. Should you find this biological medication not effective or the side effects too overwhelming, what is your next step? Have you discussed this with your rheumatologist? You know what they say, knowledge is power. Here is a link to read up on the different biologics I hope it helps and doesn't overwhelm you. I trialed 5 and finally stumbled upon one that worked for my axspa pain and enthesitis. It was tough sailing, but slow and steady I found relief. Here are some links as well to forums and articles relating to Humira. I wish you all the relief possible. Rebecca