I have gotten injections in a few places, my neck, my lumbar area, my ankle, and my hands. The injections in my neck and lumbar at first lasted a few months, then began only lasting maybe 4- 6 weeks, then not at all - had surgery. The relief wasn't instant but it did lower my pain level a notch or two in the beginning. The ankle and hands are a different story. They were so painful and injections didn't help at all. Had surgery on them.