Thanks for sharing this morsel of info here in the community friend. Being HLA-B27 negative in the context of spondyloarthritis can sometimes add complexity to the diagnosis, but it's important to remember that spondyloarthritis is a group of related conditions, and not all of them are HLA-B27 positive. While HLA-B27 can be a helpful marker, it's not the sole determinant for diagnosing these conditions. How are you feeling currently? Have you had any hurtles when it comes to treatment or the disease? Wishing you well. Rebecca (community moderator)