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Biologics Side Effects

I recently started biologic injections (Cosentyx) to help manage my axSpA. 2 days after my injection I get flu like symptoms (nausea, headache, brain fog, fatigue). This seems to pass after the 3rd or 4th day. Does anyone else experience this or have helpful tips to help mitigate the side effects?

  1. My rheumatologist tried MTX and several TNFi meds to tame my my evil eye inflammation, but with little success. Then came Cosyntex, which caused rashes and nasal breathing problems. That’s when I switched to Rituxan. The rashes and nasal cleared… but

    1. Thanks so much for joining in the conversation. Sorry to hear that your uveitis has been difficult to manage with biologics and other meds only to be met with failure and/or side effects. How has the use of the Rituxan been? I hope you've found some results. Many times finding an effective treatment plan can take time during the trial period. It can be frustrating. Wishing you the best as you tackle these meds. Rebecca (team member)

  2. I was on Inflectra for several years after changing from Remicade. I did alright except the day of infusion I would have a huge wave of exhaustion and also headaches. I live in a small town & thought I could shop at some stores where my infusion suite is after but nope. I had a reaction my last 2 infusions so I’m waiting to see what Medicare covers before trying a new med. Good luck Emme1. I think it’s a risk vs reward scenario in my mind.

    1. ,
      Thanks so much for sharing your experience.
      Sending you positive thoughts that you find the right "fit".
      Please keep us updated.
      ~Doreen (Team Member)

  3. ,
    I just wanted to check in and see how things are going today.
    It probably goes without saying that while biologics have proven to be highly effective, they do come with some side effects including upper respiratory infections, pneumonia, and urinary tract infections (just to name a few).
    As Rebecca mentioned, we have heard from others in the community who have mentioned flu-like symptoms after taking biologics. We always recommend sharing any new or changing symptoms with your healthcare provider.
    In addition, there is no "one-size fits all" when it comes to biologics, many in this community have gone through more than one to find the right "fit".
    Wishing you all the best, Doreen (Team Member)

    1. - Thanks for posting, and welcome. I'm sorry you are feeling like this following injections. From what I understand a few in the community have had this occur. I wanted to stop by to say hello and leave a link to an article that may help - https://axialspondyloarthritis.net/living/humira-flu If these symptoms continue, you may wish to inform your prescribing physician. It may be that this specific biological medication is not optimal for you. Wishing you the best. Rebecca (team member)

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