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HLA-B27 Gene

I have been diagnosed with Psoriatic Arthritis that my rheumatologist says might be AS instead. The jury is still out. However, I do not have the HLA-B27 gene, and I was curious if there are others out there with AS or PsA who also do not have this gene?

  1. I have AS and am also HLA-B27 negative. I think they're learning there are other genes involved so HLA-B27 shouldn't be as much of a determining factor as it used to be.

  2. Hi hope you are keeping well.


    I have AS and I am HLA-B27 negative!


    Here is a forum that I started some time ago about this gene, you can read it here and read people's comments https://ankylosingspondylitis.net/forums/are-you-hla-b27-positive-or-negative


    If you've any questions please ask,
    Ali (Community Member)

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