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What biologics have you tried and how have they helped?

Please remember that everyone is different, and what works for some may not work for others. Please respect everyone's experience and their decisions to try or not try certain medications.

  1. SECUKINUMAB

  2. 18 years on remicade and then it completely stopped working. Remicade was great until the last 6 months on it when I started to have major flares.
    Now on simponi and doing well

    1. 18 years is a long run with a medication! I can only imagine how hard it was for you once it stopped working. I’m glad to hear Simponi is helping and you’re doing well with it! -Latoya (Team Member)

  3. I have heard that semi glue tides have helped with pain. Has anyone taken those?

    1. I've failed my last 5 biologics. I'd get maybe a year and they stopped working. I started Mounjaro in January because my A1c was elevated. Slowly, once I got past the first few weeks and the stomach side effects, I started to feel better. I'm getting actual relief from my enthesitis! My shoulders, collar bones, hands and achilles no longer hurt. Yeah the back pain and foot pain is still there, but it's a vast improvement over what it was. I didn't expect it, but I'm thrilled!

    2. Thank you for sharing your experience. Living with two serious conditions at the same time is very challenging, but it's great that a treatment for one helped the other! Mounjaro is use to treat elevated blood sugar and diabetes, but I don't see much online connecting AS with blood sugar. The NIH, however, reports that there is a higher risk of diabetes with AS. Does anyone know any more about the connection? All the best, Kathy (Team member)

  4. I’ve been on remicade Enbryl and couple others short term I’m now on rinvoq pain is now not manageable I have been on meloxicam for over 15 years. I’m now starting to have stomach problems and losing blood somewhere so having iron infusions, I will say the meloxicam helps but now I do not know what to do in either. Does my rheumatologist.

    1. I’ve used Celebrex 200 two times a day with Tylenol extended release 1350 2 times a day, that helps me keep manageable

    2. did celebrex cause weight gain

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