I've failed my last 5 biologics. I'd get maybe a year and they stopped working. I started Mounjaro in January because my A1c was elevated. Slowly, once I got past the first few weeks and the stomach side effects, I started to feel better. I'm getting actual relief from my enthesitis! My shoulders, collar bones, hands and achilles no longer hurt. Yeah the back pain and foot pain is still there, but it's a vast improvement over what it was. I didn't expect it, but I'm thrilled!