Yes, I suffer from on/off gastro symptoms. It comes and goes for months at a time. At this moment I am feeling OK with little discomfort or pain in my gut. I am trialling specific supplements recommended by a dietician but not really finding any benefit in doing this just yet. The gut symptoms + calprotectin levels pointed to IBD and was fully investigated earlier this year prior to starting first biologic. Fortunately there wasn’t any identifiable damage to my stomach or intestinal tract. That’s good news, right? The GI consultant suggested the gut symptoms could be the result of years of Anti-inflammatories and Opiate usage. I reduced the amount of Etoricoxib from 120mg to 90mg per day and increased Omeprazole to 40mg per day. That definitely reduced the severity of the gut symptoms during a flare up.