Hi, This is Shelley. Has anyone had problems getting a biosimiliar approved for 1x each week for Humira? Mine was denied but my Dr. Is appealing. If the appeal is a no, we may try methotrexate. I am in so much pain. So many joints hurt-even my jaw. I am also having problems with my eyes being inflamed (going to eye Dr). This horrible flare has been going on for a year. How have people felt on methotrexate? Horrible side effects? I am scared, but willing to try anything at this point. I am on 12 mg Prednisone but have very bad Osteo. It's a Nightmare I can't wake up from. Thanks for listening. Shell