Thanks Kathy. I haven't asked the doc about it yet because I'm unsure if the med did actually cause more heartburn. It seems to be getting better. I'm going to see if it happens again on the second dose which is due in a few days. I have noticed that my hip/thigh/buttock/lower back is no longer tender and painful. And my eustachian tube dysfunction seems better too! I had thought I could try getting off Celebrex, but I felt a bit stiff after skipping it one day, so going to stay on it for now. I'm trying to be patient, but I am hopeful at the results so far after only one dose.